The mRNA Research Associate to Principal Scientist will develop methods to synthesize, purify, and scale up mRNA production. The incumbent will also develop and use methods to quality control mRNA and lead the optimization of Vernal’s plasmid and mRNA processes through innovative research and development.

Responsibilities

• Develop and optimize mRNA synthesis reactions

• Develop and apply analytical methods to mRNA

• Create and optimize plasmid and mRNA synthesis workflows

• Maintain stock of critical reagents and supplies, and inventory of plasmids and mRNA

• Become an essential part of Vernal’s origin story

Requirements and Desirable skills

• Persistence, determination, client- and team-first mindset

• Bachelor’s to Ph.D. degree in cell or molecular biology, biomedical or chemical engineering, biochemistry, or a related field

• mRNA: synthesis and purification, working knowledge of mRNA biology (e.g. sequence, structure)

• Molecular biology: Polymerase chain reaction (PCR), qPCR, RT-PCR, molecular cloning (e.g. Golden Gate), gel electrophoresis, E. coli culture, plasmid purification, Fragment Analyzer

• Cell biology: cell line and primary cell culture maintenance, expansion, banking; transfection optimization

• Automation experience will be a differentiator

• Optimization through design of experiments and statistical modeling (e.g. JMP)

• Deep understanding and practical knowledge of the scientific method and selection of experimental controls

• High attention to detail including planning, executing, and documenting experiments

• Communication skills including protocol writing, working directly with clients, Power Point

How to apply

Please email your resume and cover letter to careers@vernal.bio.